周洲，研究员，博士研究生导师，现任阜外医院实验诊断中心主任, 心血管疾病预警及诊断北京市重点实验室主任。获得中南大学湘雅医学院临床医学学士，美国贝勒医学院(Baylor College of Medicine)心血管科学博士。2014年入选国家级高层次引进人才青年项目， 2019年获评全国“向上向善”好青年荣誉称号，2024年获得国家杰出青年科学基金，2025年获得国自然重大项目基金。2012年底以引进人才加入院校，曾在美国华盛顿大学医学院血液中心研究所(Puget Sound Blood Center)任研究科学家。

本人回国后创建阜外医院分子诊断中心，聚焦遗传性心血管疾病机制研究、分子诊断及技术转化。带领团队搭建前沿检测平台，2015 年牵头获批“心血管疾病分子诊断北京市重点实验室”并任主任，2016年整合医院检验科、分子诊断科与病理科，成立实验诊断中心并任主任。深耕遗传性心血管疾病领域，以第一或通讯作者在Circulation、Circulation Research等权威期刊发表论文80余篇，主持20余项国家重点研发计划和国自然重大项目，获国际血栓与止血会议青年科学家主席奖。

1.Xuanyu Liu#, Qingyi Zeng#, Hang Yang, Wenke Li, Qianlong Chen, Kunlun Yin, Zhang Pan, Kai Wang,* Mingyao Luo,* Chang Shu* and Zhou Zhou*. Single-Nucleus Multiomic Analyses Identifies Gene Regulatory Dynamics of Phenotypic Modulation in Human Aneurysmal Aortic Root. Advanced Science,2024 Jun;11(22):e2400444. (IF=14.3)

2.Xuanyu Liu#, Zhujun Li#, Hayson Chenyu Wang, Meng Yuan, Jie Chen, Jiuzuo Huang, Nanze Yu, Zhou Zhou* and Xiao Long*. Single-cell RNA sequencing identifies inherent abnormalities of adipose-derived stem cells from nonlesional sites of patients with localized scleroderma. Cellular & Molecular Biology Letters， 2024 Aug 30;29(1):115. (IF=10.2)

3.Weizhen Zhou#, Wenke Li#, Huayan Shen#, Ruby W. Wang, Wen Chen, Yujing Zhang, Qingyi Zeng, Hao Wang, Meng Yuan, Ziyi Zeng, Jinhui Cui, Chuanyun Li, Fred Y. Ye*, Zhou Zhou*. CHDbase: A comprehensive knowledgebase for congenital heart disease-related genes and clinical manifestations. Genomics, Proteomics & Bioinformatics 2023, 21(1):216-227. (IF=9.5)

4.Xuanyu Liu#, Kunlun Yin#, Liang Chen#, Wen Chen, Wenke Li, Taojun Zhang, Yang Sun, Meng Yuan, Hongyue Wang, Yunhu Song, Shuiyun Wang*, Shengshou Hu*, Zhou Zhou*. Lineage-specific regulatory changes in hypertrophic cardiomyopathy unraveled by single-nucleus RNA-seq and spatial transcriptomics. Cell Discovery 2023, 9(1):6. (IF=33.5)

5.Weizhen Zhou#*, Yujing Zhang#, Guoyan Zhu#, Huayan Shen, Qingyi Zeng, Qianlong Chen, Wenke Li, Mingyao Luo, Chang Shu, Hang Yang*, Zhou Zhou*. HTAADVar: Aggregation and fully automated clinical interpretation of genetic variants in heritable thoracic aortic aneurysm and dissection. Genetics in Medicine 2022, 24(12): 2544-2554. (IF=8.8)

6.Xuanyu Liu#, Meng Yuan#, Qinqin Xiang, Zhujun Li, Fen Xu, Wen Chen, Jie Chen, Jiuzuo Huang, Nanze Yu, Zhou Zhou* and Xiao Long*. Single-cell RNA sequencing of subcutaneous adipose tissues identifies therapeutic targets for cancer-associated lymphedema. Cell Discovery 2022, 8(1): 58. (IF=38.097)

7.Xuanyu Liu#, Wen Chen#, Guoyan Zhu#, Hang Yang, Wenke Li, Mingyao Luo, Chang Shu* and Zhou Zhou*. Single-cell RNA sequencing identifies an Il1rn(+)/Trem1(+) macrophage subpopulation as a cellular target for mitigating the progression of thoracic aortic aneurysm and dissection. Cell Discovery 2022, 8(1): 11. (IF=38.097)

8.Chen, Wen#; Liu, Xuanyu*; Li, Wenke; Shen, Huayan; Zeng, Ziyi; Yin, Kunlun; Priest, James R.; Zhou, Zhou*. Single-cell transcriptomic landscape of cardiac neural crest cell derivatives during development. EMBO Reports 2021, 22(11): e52389. (IF=9.071)

9.Xuanyu Liu#, Wen Chen#, Wenke Li, James R. Priest, Yuanyuan Fu, Kunjing Pang, Baihui Ma, Bianmei Han, Xuewen Liu, Shengshou Hu*, Zhou Zhou*. Exome-based Case-control analysis highlights the pathogenic role of ciliary genes in transposition of the great arteries. Circulation Research 2020, 126(7): 811-821. (IF=14.467)

10.Xuanyu Liu#, Wen Chen, Wenke Li,Yan Li, James R. Priest,Bin Zhou, Jikui Wang*, Zhou Zhou*. Single-cell RNA-seq of the developing cardiac outflow tract reveals convergent development of the vascular smooth muscle cells. Cell Reports 2019, 28(5):1346-1361. (IF=7.815)